Milind Kashinath Patel ¹and Swapnil Ghanshyam Dhake ²✉
¹Poojya Sane Guruji Vidya Prasarak Mandal’s S. I. Patil Arts
Patel Science and Shahada Taluka Kharedi Vikri Sangh Commerce College,
Shahada, Dist-Nandurbar (M.S), India-425409.
²Department of Engineering Sciences and Humanities,
Sandip Foundation’s Sandip Institute of Technology & Research Centre
Mahiravani, Trimbak Road, Nashik (M.S.), India-422213.
Received: Feb 21, 2023/ Revised: Mar 10, 2023/Accepted: Mar 14, 2023
(✉) Corresponding Author: swapnill.dhake5@gmail.com
Abstract
Corchorus depressus (L.) is a member of the Tiliaceae family, which has over 100 different species. Due to isolated phytochemicals, potential biological activity and therapeutic value, Corchorus depressus (L.) whole plant study proved promising. The current research sought to investigate the biologically active substances found in solvent extracts of Corchorus depressus (Linn.) leaves. The active substances were isolated by cold maceration method using petroleum ether followed by chloroform, methanol, and ethanol and identified by the phytochemical test. The biological effects of solvent extracts, including their antibacterial, antifungal, antioxidant, and anti-inflammatory potential, were also studied. The investigation of various solvent extracts revealed that active chemicals like sterols, triterpenes, carbohydrates, glycosides, flavonoids, alkaloids, tannins, amino acids, and proteins were present. The evaluation of leaf powder was supported by physicochemical analysis. Biological screening of four solvent extracts showed substantial anti-oxidant and antimicrobial potential. Extracts from the leaves of Corchorus depressus (L.) showed high biological activity, and a significant number of secondary metabolites were discovered through preliminary phytochemical analysis studies.
Keywords: Corchorus depressus, phytochemical test, pharmacognostic study, biological activity
References
Afzal, S., Chaudhary, B. A., Ahmad, A., & Afzali, K. (2015). Prelimiary phytochemical analysis and antifungal activities of crude extracts of Zaleya pentandra and Corchorus depressus Linn. Acta Pol Pharm, 72, 329-34.
Ahmad, S., Wariss, H. M., Alam, K., Anjum, S., & Mukhtar, M. (2014). Ethnobotanical studies of plant resources of Cholistan desert, Pakistan. Int J Sci Res, 3(6), 1782-1788.
Ahmad, V. U., Ali, A., Ali, Z., Baqai, F. T., & Zafar, F. N. (1998). Cycloartane triterpene glucosides from Corchorus depressus. Phytochemistry, 49(3), 829-834.
Ahmad, V. U., Ali, A., Ali, Z., Zafar, F. N., & Zahid, M. (2000). Novel cycloartane saponins from Corchorus depressus L. Chemical and pharmaceutical bulletin, 48(11), 1597-1601.
Ed Murray, P. R., Baron, E. J., Jorgensen, J. H., Landery, M. L., Pflaller, M. A. (2007). 1152-1173.
Elizabeth, K. M., Suryanarayana, R. (2006). Antimicrobial activity-Aristolochia bracteta. Asian Journal of Chemistry, 18(1):207-211.
Espinel-Ingroff, M. A. (2007). Pfaller, Susceptibility test methods: yeasts and filamentous fungi. in: Murray, PR; Baron, EJ; Jorgensen, JH; Landry, ML; Pfaller (Eds.) MA Manual of Clinical Microbiology, ninth ed. vol. II, American Society for Microbiology, Washington, DC, USA.
Herborne, J. B. (1973). Phytochemical methods. A guide to modern techniques of plant analysis, 2, 5-11.
Ikram, M., Khattak, S. G., & Gilani, S. N. (1987). Antipyretic studies on some indigenous Pakistani medicinal plants: II. Journal of ethnopharmacology, 19(2), 185-192. https://doi.org/10.1016/0378-8741(87)90040-7
Jabeen, Z., Bukhari, I. H., Qurat-ul-ain, S. P., Aslam, N., & Kamal, S. (2014). Mineral profile, antioxidant and antimicrobial studies of Corchorous depressus leaves. Energy J, 43.
Jain, A., Katewa, S. S., Chaudhary, B. L., & Galav, P. (2004). Folk herbal medicines used in birth control and sexual diseases by tribals of southern Rajasthan, India. Journal of ethnopharmacology, 90(1), 171-177.
Jayaveera, K. N., Yoganandham, R. K., Govindarajula, Y., & Kumanan, R. (2010). Phytochemical screenings, antibacterial activity and physico chemical constants of ethanolic extract of Euphorbia thymifolia Linn. Int J Pharm Pharm Sci, 2(3), 81-82.
Jorgensen, J. H., & Turnidge, J. D. (2015). Susceptibility test methods: dilution and disk diffusion methods. Manual of clinical microbiology, 1253-1273.
Kakrani, H. N., & Saluja, A. K. (2001). Plants used for diuretic activity in traditional medicine in Kutch district, Gujarat. Journal of natural remedies, 121-124.
Kar, B., Kumar, R. S., Karmakar, I., Dola, N., Bala, A., Mazumder, U. K., & Hadar, P. K. (2012). Antioxidant and in vitro anti-inflammatory activities of Mimusops elengi leaves. Asian Pacific Journal of Tropical Biomedicine, 2(2), S976-S980.
Khan, M. S., Javed, K., Khan, M. H., Shamsi, M. A., & Siddiqui, A. A. (1991). α-Amyrin derivatives from Corchorus depressus. Phytochemistry, 30(6), 1989-1992.
Kumar, K. T., Nanda, U. N., Kumar, S. A. (2017). Antiinflammatory activity of methanolic extract of Corchorus depressus (L.) Stocks. MIT International Journal of Pharmaceutical Sciences, 3(1), 16–20.
Kumar, K. T., Nanda, U. N., Kumar, S. A. (2017). Evaluation of Analgesic, antipyretic and anti-lipid peroxidative activity of medico-religious plant found in the state of Odisha, India’, World Jour. of Pharm. & pharmaceutical sciences., 6(1):619-636.
Lu, Y., Shipton, F. N., Khoo, T. J., & Wiart, C. (2014). Antioxidant activity determination of citronellal and crude extracts of Cymbopogon citratus by 3 different methods. Pharmacology & Pharmacy, 2014. http://dx.doi.org/10.4236/pp.2014.54047
Manjunath, K. P., Kulkarni, G. T., & Patil, K. S. (2006). Preliminary Phytochemical investigation and wound healing activity of the root of Swertia chirata Buch. Ham (gentianaceae). INDIAN DRUGS-BOMBAY-, 43(7), 535.
Naz, R., & Bano, A. (2012). Antimicrobial potential of Ricinus communis leaf extracts in different solvents against pathogenic bacterial and fungal strains. Asian Pacific journal of tropical biomedicine, 2(12), 944-947. https://doi.org/ 10.1016/S2221-1691(13)60004-0
Pareek, A., Yadav, S. K., Deasai, P., Godavarthi, A., & Nagori, B. P. (2013). Antioxidative and hepatoprotective effect of Corchorus depressus L. against CCl 4-induced toxicity in rats. Pharmacognosy Communications, 3(3).
Pharmaceutical Sciences, 3(1):16–20.
Raza, M. A., Younas, M., Buerkert, A., & Schlecht, E. (2014). Ethno-botanical remedies used by pastoralists for the treatment of livestock diseases in Cholistan desert, Pakistan. Journal of ethnopharmacology, 151(1), 333-342. http://nbn-resolving.de/urn:nbn:de:hebis:34-2016092050900
Sadashivam, S., Manickam, A. (2005). Biochemical methods. Edn.3, New Age International Limited, Publishers, New Delhi, 1-4.
Sharma, M. P., Ahmad, J., Hussain, A., & Khan, S. (1992). Folklore medicinal plants of Mewat (Gurgaon district), Haryana, India. International journal of pharmacognosy, 30(2), 129-134. https://doi.org/10.3109/13880209209053975.
Sheorain, J., Mehra, M., Thakur, R., Grewal, S., & Kumari, S. (2019). In vitro anti-inflammatory and antioxidant potential of thymol loaded bipolymeric (tragacanth gum/chitosan) nanocarrier. International journal of biological macromolecules, 125, 1069-1074. https://doi.org/10.1016/j.ijbiomac.2018.12.095
Singh, A. K., Raghubanshi, A. S., & Singh, J. S. (2002). Medical ethnobotany of the tribals of Sonaghati of Sonbhadra district, Uttar Pradesh, India. Journal of ethnopharmacology, 81(1), 31-41. https://doi.org/10.1016/s0378-8741(02)00028-4
The Unani pharmacopeia of India, Department of AYUSH, Ministry of Health & Family welfare, Government of India. 2007-2010.
Upadhyay, B., Dhaker, A. K., & Kumar, A. (2010). Ethnomedicinal and ethnopharmaco-statistical studies of Eastern Rajasthan, India. Journal of Ethnopharmacology, 129(1), 64-86. https://doi.org/10.1016/j.jep.2010.02.026
How to cite this article
Patel, M. K. and Dhake, S. G. (2023). Preliminary Phytochemical, Physicochemical and Biological Study of Corchorus depressus (Linn) leaves. Microbial Science Archives, Vol. 3(1), 32-37. https://doi.org/10.47587/MSA.2023.3106
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